Medicare local coverage
Medicare coverage for MolDX: Molecular Testing for Identification and Management of Hereditary Transthyretin Amyloidosis (LCD)
4 Medicare Administrative Contractors publish a local coverage determination (LCD) for MolDX: Molecular Testing for Identification and Management of Hereditary Transthyretin Amyloidosis. The snapshot lists 5 LCD records: 4 active, 1 retired.
An LCD applies only in the jurisdiction of the contractor that wrote it. Two contractors can cover the same service with different criteria, documentation requirements and covered diagnoses, so check the LCD from the contractor that processes your claims.
LCDs by contractor
| Contractor | LCD | Status | Last updated |
|---|---|---|---|
CGS Administrators, LLCMAC - Part A, MAC - Part B | L39940 | Active | Mar 10, 2026 |
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B | L39950 | Retired Feb 5, 2026 | Feb 5, 2026 |
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B | L39948 | Active | Jan 26, 2026 |
Palmetto GBAMAC - Part A, MAC - Part B | L39935 | Active | Jun 25, 2025 |
WPS Insurance CorporationMAC - Part A, MAC - Part B | L39987 | Active | Jun 25, 2025 |
An LCD marked Future has been finalized and is in its notice period; it applies from the effective date shown. LCD IDs link to the record on cms.gov.
Billing and coding articles
The codes live in the billing and coding article that goes with each LCD: the CPT and HCPCS codes the policy applies to, the ICD-10 codes that support medical necessity, and any modifier or documentation rules.
- A59849Palmetto GBAUpdated Sep 15, 2026
- A59862CGS Administrators, LLCUpdated Oct 13, 2026
- A59872Noridian Healthcare Solutions, LLCUpdated Sep 15, 2026
- A59874Noridian Healthcare Solutions, LLCUpdated Feb 5, 2026
- A59906WPS Insurance CorporationUpdated Sep 17, 2026
CMS also lists 5 response-to-comments articles for this topic, where contractors answer public comments on the proposed LCD: A60190, A60191, A60201, A60202, A60219.
Check claim lines against Medicare coverage
Coverage Check tells you whether a claim's diagnoses support Medicare LCD or NCD coverage for each procedure line, and shows the policy and CMS source behind each answer.
Related LCD topics
- MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
- Bariatric Surgical Management of Morbid Obesity
- Bowel Management Devices
- Endovascular Management for Peripheral Arterial Disease of the Upper and Lower Extremities
- Epidural Steroid Injections for Pain Management
- Facet Joint Interventions for Pain Management
All Medicare LCD topics · National coverage determinations · Payer policies by payer
Source: CMS Medicare Coverage Database, via the public CMS Coverage API, snapshot Oct 25, 2026. LCDs change between snapshots; confirm the version in effect for your date of service on cms.gov before billing.