Medicare local coverage
Medicare coverage for MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing (LCD)
4 Medicare Administrative Contractors publish a local coverage determination (LCD) for MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing. The snapshot lists 5 LCD records: 4 active, 1 retired.
An LCD applies only in the jurisdiction of the contractor that wrote it. Two contractors can cover the same service with different criteria, documentation requirements and covered diagnoses, so check the LCD from the contractor that processes your claims.
LCDs by contractor
| Contractor | LCD | Status | Last updated |
|---|---|---|---|
CGS Administrators, LLCMAC - Part A, MAC - Part B | L39038 | Active | Apr 6, 2026 |
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B | L39003 | Retired Feb 5, 2026 | Feb 5, 2026 |
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B | L39001 | Active | Jan 26, 2026 |
Palmetto GBAMAC - Part A, MAC - Part B | L38988 | Active | Jun 25, 2025 |
WPS Insurance CorporationMAC - Part A, MAC - Part B | L39044 | Active | Jun 18, 2026 |
An LCD marked Future has been finalized and is in its notice period; it applies from the effective date shown. LCD IDs link to the record on cms.gov.
Billing and coding articles
The codes live in the billing and coding article that goes with each LCD: the CPT and HCPCS codes the policy applies to, the ICD-10 codes that support medical necessity, and any modifier or documentation rules.
- A58710Palmetto GBAUpdated Jul 28, 2026
- A58720Noridian Healthcare Solutions, LLCUpdated Jul 28, 2026
- A58726Noridian Healthcare Solutions, LLCUpdated Feb 24, 2026
- A58747CGS Administrators, LLCUpdated Jul 2, 2026
- A58761WPS Insurance CorporationUpdated Jul 31, 2026
CMS also lists 5 response-to-comments articles for this topic, where contractors answer public comments on the proposed LCD: A59005, A59007, A59017, A59018, A59020.
Check claim lines against Medicare coverage
Coverage Check tells you whether a claim's diagnoses support Medicare LCD or NCD coverage for each procedure line, and shows the policy and CMS source behind each answer.
Related LCD topics
- Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
- MolDX: Molecular Testing for Identification and Management of Hereditary Transthyretin Amyloidosis
- Endovascular Management for Peripheral Arterial Disease of the Upper and Lower Extremities
- Genetic Testing for Cardiovascular Disease
- Genomic Sequence Analysis Panels in the Treatment of Hematolymphoid Diseases
- Genomic Sequence Analysis Panels in the Treatment of Solid Organ Neoplasms
All Medicare LCD topics · National coverage determinations · Payer policies by payer
Source: CMS Medicare Coverage Database, via the public CMS Coverage API, snapshot Oct 25, 2026. LCDs change between snapshots; confirm the version in effect for your date of service on cms.gov before billing.