Medicare local coverage
Medicare coverage for MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms (LCD)
4 Medicare Administrative Contractors publish a local coverage determination (LCD) for MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms. The snapshot lists 5 LCD records: 4 active, 1 retired.
An LCD applies only in the jurisdiction of the contractor that wrote it. Two contractors can cover the same service with different criteria, documentation requirements and covered diagnoses, so check the LCD from the contractor that processes your claims.
LCDs by contractor
| Contractor | LCD | Status | Last updated |
|---|---|---|---|
CGS Administrators, LLCMAC - Part A, MAC - Part B | L40000 | Active | Jun 8, 2026 |
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B | L39927 | Retired Feb 5, 2026 | Feb 5, 2026 |
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B | L39923 | Active | Jan 26, 2026 |
Palmetto GBAMAC - Part A, MAC - Part B | L39919 | Active | Jun 27, 2025 |
WPS Insurance CorporationMAC - Part A, MAC - Part B | L40022 | Active | Jun 27, 2025 |
An LCD marked Future has been finalized and is in its notice period; it applies from the effective date shown. LCD IDs link to the record on cms.gov.
Billing and coding articles
The codes live in the billing and coding article that goes with each LCD: the CPT and HCPCS codes the policy applies to, the ICD-10 codes that support medical necessity, and any modifier or documentation rules.
- A59827Palmetto GBAUpdated Nov 10, 2025
- A59835Noridian Healthcare Solutions, LLCUpdated Jan 26, 2026
- A59837Noridian Healthcare Solutions, LLCUpdated Feb 5, 2026
- A59919CGS Administrators, LLCUpdated Nov 14, 2025
- A59939WPS Insurance CorporationUpdated Nov 18, 2025
CMS also lists 4 response-to-comments articles for this topic, where contractors answer public comments on the proposed LCD: A60223, A60227, A60228, A60248.
Check claim lines against Medicare coverage
Coverage Check tells you whether a claim's diagnoses support Medicare LCD or NCD coverage for each procedure line, and shows the policy and CMS source behind each answer.
Related LCD topics
- MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Targeted Therapy in Cancer
- MolDX: Next-Generation Sequencing for Solid Tumors
- MolDX: Next-Generation Sequencing Lab-Developed Tests for Myeloid Malignancies and Suspected Myeloid Malignancies
- Allogeneic Hematopoietic Cell Transplantation for Primary Refractory or Relapsed Hodgkin and Non-Hodgkin Lymphoma with B-cell or T-cell Origin
- Allogeneic Hematopoietic Cell Transplantation for Primary Refractory or Relapsed Hodgkin's and Non-Hodgkin's Lymphoma with B-cell or T-cell Origin
- Amniotic and Placental-Derived Product Injections and/or Applications for Musculoskeletal Indications, Non-Wound
All Medicare LCD topics · National coverage determinations · Payer policies by payer
Source: CMS Medicare Coverage Database, via the public CMS Coverage API, snapshot Oct 25, 2026. LCDs change between snapshots; confirm the version in effect for your date of service on cms.gov before billing.