Medicare local coverage

Medicare coverage for MolDX: MGMT Promoter Methylation Analysis (LCD)

4 Medicare Administrative Contractors publish a local coverage determination (LCD) for MolDX: MGMT Promoter Methylation Analysis. The snapshot lists 5 LCD records: 4 active, 1 retired.

An LCD applies only in the jurisdiction of the contractor that wrote it. Two contractors can cover the same service with different criteria, documentation requirements and covered diagnoses, so check the LCD from the contractor that processes your claims.

LCDs by contractor

ContractorLCDStatusLast updated
CGS Administrators, LLCMAC - Part A, MAC - Part B
L36113ActiveJul 2, 2026
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B
L36192Retired Jan 22, 2026Jan 22, 2026
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B
L36188ActiveJan 12, 2026
Palmetto GBAMAC - Part A, MAC - Part B
L35974ActiveOct 7, 2021
WPS Insurance CorporationMAC - Part A, MAC - Part B
L37001ActiveSep 15, 2025

An LCD marked Future has been finalized and is in its notice period; it applies from the effective date shown. LCD IDs link to the record on cms.gov.

Billing and coding articles

The codes live in the billing and coding article that goes with each LCD: the CPT and HCPCS codes the policy applies to, the ICD-10 codes that support medical necessity, and any modifier or documentation rules.

  • A56941Palmetto GBAUpdated Oct 7, 2021
  • A56983CGS Administrators, LLCUpdated Aug 14, 2024
  • A57432Noridian Healthcare Solutions, LLCUpdated Jan 12, 2026
  • A57433Noridian Healthcare Solutions, LLCUpdated Mar 9, 2026
  • A57577WPS Insurance CorporationUpdated Aug 23, 2023

CMS also lists 2 response-to-comments articles for this topic, where contractors answer public comments on the proposed LCD: A54895, A54896.

Check claim lines against Medicare coverage

Coverage Check tells you whether a claim's diagnoses support Medicare LCD or NCD coverage for each procedure line, and shows the policy and CMS source behind each answer.

Related LCD topics

All Medicare LCD topics · National coverage determinations · Payer policies by payer

Source: CMS Medicare Coverage Database, via the public CMS Coverage API, snapshot Oct 25, 2026. LCDs change between snapshots; confirm the version in effect for your date of service on cms.gov before billing.